Director, Real-World Biostatistics – GSK
Sites: USA – Pennsylvania – Philadelphia, Belgium – Wavre, UK – London, USA – Massachusetts – Waltham, USA – North Carolina – Durham.
Posted on: Nov 13 2025
Overview
As a key leader in Real-World Evidence, the Director will advance strategy and methodology across the drug and vaccine development lifecycle using RWD. The role focuses primarily on oncology research units and requires deep biostatistical expertise, strategic insight, and methodological innovation to support product development and commercialization.
Responsibilities
* Lead and oversee execution of real‑world studies, ensuring methodological rigor, quality control, and regulatory compliance.
* Create and refine statistical analysis plans, conduct complex analyses, and communicate findings to internal and external stakeholders.
* Apply fit‑for‑purpose non‑interventional statistical methods tailored to specific objectives, ensuring robust data interpretation.
* Maintain in‑depth therapeutic area knowledge, including data source selection and technical specification documentation.
* Mentor junior staff, guiding professional growth and fostering a collaborative environment.
* Manage statistical efforts for projects, including timelines, resources, quality control, and cross‑department coordination.
* Engage in strategic communication, presenting insights at conferences, publications, and stakeholder meetings.
* Stay informed on industry trends, integrate emerging biostatistical methods, and contribute to methodological research.
* Provide expertise on RWD during regulatory submissions, ensuring alignment with regulatory standards.
Qualifications
Basic
* Ph.D. in Biostatistics, Statistics, Epidemiology or related field with 8+ years (or Masters +10 years) in pharmaceutical/biotech industry, preferably in real‑world evidence, epidemiology, or health outcomes.
* Experience with drug development processes and innovative statistical approaches to meet project objectives.
* Leadership experience in pharmacoepidemiology/health outcomes analytics using RWD (e.g., EHR, insurance claims, registries).
* Proficiency in R, Python and applied experience with observational data.
* Experience working under regulatory requirements for RWD and clinical trials.
* Project management skills delivering results in matrixed environments.
* Methodological research contributions to real‑world data analytics publications.
Preferred
* Experience with causal inference methods (propensity score, doubly robust, TMLE, instrumental variables, time‑varying exposures).
* Time‑to‑event analysis in non‑randomized settings.
* Machine learning expertise.
* Excellent communication and interpersonal skills.
* Fluency in written and spoken English.
Compensation & Benefits
US annual base salary: $174,900 – $291,500 (location and experience dependent). Benefits include annual bonus, share‑based long‑term incentive, health insurance, retirement plans, paid holidays, vacation, caregiver/parental leave, and medical leave.
About GSK
GSK is a global biopharma company focused on science, technology, and talent to advance disease prevention and treatment. We operate in respiratory, immunology, oncology, HIV, and infectious disease sectors and aim to improve the health of 2.5 billion people.
Equal Opportunity & Accessibility
GSK is an Equal Opportunity Employer. We ensure that all qualified applicants receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information, military service or any basis prohibited under federal, state or local law.
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