Department
You will join our client's Advanced Material Characterization and Investigations (AMCI) group within the Analytical Development (AD) department. AMCI is an international and diverse team of scientists performing advanced analytical characterization of pharmaceutical products and leading global analytical investigations for the commercial product portfolio and for the Discovery, Product Development & Supply (DPDS) organization.
Within AMCI, the Advanced Molecular Analysis (AMA) team is a group of analytical centers of excellence in structure elucidation (by high-resolution mass spectrometry and NMR), organic and inorganic trace analysis, polymer characterization, and ADC, oligonucleotide & peptide analytics.
Role
We are currently recruiting a skilled and enthusiastic Organic Chemist to join our client's AMA team, where you will play a crucial role in our mission to quantify nitrosamines in various matrices and pharmaceutical products. This laboratory-based position offers you the opportunity to develop and implement innovative analytical test methods for nitrosamines, utilizing your strong background in chemistry and mass spectrometry. In this role, you will also collaborate closely with internal specialists to conduct thorough root cause investigations and explore innovative approaches for optimal analyses. If you are passionate about pushing the boundaries of analytical techniques and eager to make a significant impact in the field, we would love to hear from you!
Key Responsibilities
- Support method development and feasibility of analytical methods, from innovative sample preparations to cutting-edge chromatographic separations and detection, for the quantification of trace analysis impurities, in accordance with regulatory guidelines and company standards.
- Support comprehensive root cause investigations related to nitrosamines, with a focus on chemical reactivity, from the early stages through to late development within our R&D portfolio.
- Collaborate closely with cross-functional teams, demonstrating your ability to learn rapidly and explore innovative techniques.
- Initiate and lead partnerships with universities and other research institutions to expand our external innovation network, fostering collaboration that enhances our capabilities and expertise.
- Maintain a safe work environment in compliance with all applicable environmental, health, regulatory requirements, GMP and safety regulations.
Qualifications
Education & Experience
- A PhD degree in organic chemistry, or related field; or a master’s degree in related science with a minimum of 6 years of experience. Work-related experience in pharmaceutical R&D is an asset.
- Proven expertise in nitrosamines chemistry is a clear asset for this role.
- Demonstrated experience in mass spectrometry, including technologies such as Triple Quadrupole and High-Resolution MS, is a significant advantage.
- Familiarity with developing chromatographic methods is preferred.
- Knowledge of regulatory frameworks (e.g., ICH, EMA, FDA) and GMP guidelines, particularly concerning validation requirements, is an advantage.
- Excellent English communication skills, both written and spoken, allowing for effective scientific discussions and collaboration
Competencies
- Fast learner with scientific curiosity, self-steering, pro-active, creative.
- Open-minded, with ability to work together as one team in a global environment.
- Good written and spoken communication and presentation skills in English.
- Efficient, flexible, dynamic, results and performance driven.
- Sense of urgency.