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Visual inspection expert

Braine-l'Alleud
Pauwels Consulting
Publiée le 28 janvier
Description de l'offre

The Visual Inspection Specialist – Process Equipment is expected to :

* Act as Subject Matter Expert (SME) for visual inspection technologies within a major CAPEX aseptic

unit project, from concept through commissioning & PV. Ensure compliance with EU GMP Annex 1

(2022 revision), robust defect detection strategy, and integration of advanced digital tools (image

analytics, AI/ML) while maintaining data integrity and connectivity with MES/eBR systems.

1. Engineering & Design :

* Define and maintain URS for visual inspection systems (manual, semi-automatic, fully automated)

including camera-based and AI-assisted solutions.

* Lead design reviews ensuring ergonomic compliance, defect classification standards, and integration

with upstream/downstream processes.

* Ensure compliance with ISO 14644 for cleanroom zones where inspection occurs and Annex 1

requirements for container integrity and particle control.

* Collaborate on layout to minimize contamination risk and optimize inspection efficiency.

2. Commissioning, Qualification & Verification (CQV) :

* Develop and execute CQV plans for visual inspection equipment including IQ/OQ/PQ and

performance verification for defect detection capability.

* Validate automated vision systems per GAMP 5 (2nd ed.) and Annex 11 requirements; ensure image

data integrity and audit trail compliance.

* Coordinate FAT/SAT with vendors; manage deviations and CAPA through eQMS.

3. Regulatory & Quality:

* Ensure visual inspection processes comply with EU GMP Annex and FDA Aseptic Processing

guidance.

* Maintain defect libraries and classification per industry standards; support trending and risk

assessments.

* Implement Data Integrity principles (ALCOA+) for image capture, storage, and review workflows.

4. Digitalization & Computerized Systems :

* Integrate visual inspection systems with MES/eBR for automated batch record updates.

* Deploy AI/ML algorithms for defect detection under Pharma 4.0 principles; validate models per GAMP 5 and CSA concepts.

* Ensure compliance with Annex 11 for computerized systems and maintain cybersecurity and access

controls.

5. Procurement & Vendor Management :

* Select and manmeetssuppliers for visual inspection equipment; ensure technical specifications and documentation meet GMP and CSV requirements.

* Benchmark emerging technologies (high-speed cameras, AI vision) and drive adoption of sustainable

solutions.

6. Leadership & Change Management :

* Promote a culture of quality and continuous improvement in visual inspection processes.

* Train operators and engineers on inspection techniques, defect recognition, and digital tools.

What are we looking for?

Requirements :

* Engineering or scientific degree (Automation, Optics,

Pharmaceutical Technology) or equivalent.

* 8+ years in pharmaceutical visual inspection systems and

aseptic operations.

* Experience with automated vision systems, defect classification,

and regulatory compliance.

* Knowledge of CSV and risk-based validation approaches (ASTM

E2500 considered an asset).

* Technical: manual/semi-automatic/automatic inspection systems, camera technology, AI/ML for

defect detection.

* Standards: EU GMP Annex, ISO 14644, GAMP 5 (2nd ed.), Annex 11, PIC/S PI 041-1.

* IT/OT: MES/eBR integration, image data management, cybersecurity.

* Soft skills: stakeholder engagement, vendor negotiation, training, and change management.

Regulatory References (knowledge required) :

* EU GMP Annex 1 – Manufacture of Sterile Medicinal Products (2022 revision).

* ISO 14644 – Cleanroom standards.

* ISPE GAMP 5 – Second Edition

* EU GMP Annex 11 – Computerised Systems.

* PIC/S PI 041-1 – Data Integrity.

* FDA Guidance – Aseptic Processing

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