Make your mark for patients
Gene Therapy Biophysical Scientist
We are looking for a Gene Therapy Biophysical Scientist who is analytical, collaborative, and solutions-oriented to join our Gene Therapy Analytical Sciences team, based at our UCB campus located in Braine-l’Alleud, Wallonia, Belgium.
About the role
You’re going to play a key role in developing and implementing biophysical analytical methods to support the CMC development of gene therapy products. You will contribute to the advancement of recombinant AAV-based therapies from early clinical phases to launch readiness, ensuring compliance with regulatory standards.
Who you will work with
You will collaborate with a multidisciplinary team across upstream/downstream/formulation operations, QC, vector biology, and external partners. You’ll be part of a dynamic and innovative environment where your expertise will directly impact UCB’s gene therapy strategy.
What you will do
1. You will develop, validate, and transfer biophysical assays for gene therapy products.
2. You will be responsible for documenting procedures, protocols, and reports with high data integrity.
3. You will manage lab activities and maintain a cutting-edge analytical environment.
4. You will support cross-functional teams and contribute to internal and external collaborations.
5. You will analyze and present results in team and project meetings.
6. You will ensure all activities comply with the relevant GMP, GSP, HSE, and biosafety standards.
Interested?
For this role, we are looking for the following education, experience, and skills:
7. Master’s degree or engineering diploma in Analytical Chemistry, Biochemistry, or equivalent with 3+ years of industrial experience.
8. Proven expertise in biophysical method development including validation; experience with rAAVs is a plus.
9. Hands-on experience with mass spectrometry and liquid chromatography.
10. Familiarity with Empower, Chromeleon, or Expressionist software is an asset.
11. Experience and/or knowledge of mass photometry is a plus
12. Strong experience of working in a regulated laboratory environment (e.g. GLP/GMP), including documentation and mastering HSE/Biosafety rules• Knowledge of ICH Q14, Q2(R2), and Analytical Quality by Design principles.
13. Strong communication, critical thinking, and problem-solving skills in a regulated lab environment.
14. Fluency in English is mandatory (written and oral)
Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!