PpJohnson Johnson Innovative Medicine develops treatments that improve the health and lifestyles of people worldwide. Our development areas encompass novel targets in neurologic disorders, gastroenterology, oncology, infectious disease, diabetes, hematology, metabolic disorders, immunologic disorders, pulmonary hypertension and reproductive medicine. /p pJob Function: Discovery Pre-Clinical/Clinical Development /p pJob Sub Function: Pharmaceutical Product RD /p pJob Category: Scientific/Technology /p pAll Job Posting Locations: Beerse, Antwerp, Belgium /p pThe successful candidate will be employed in the department of Chemical Process Research Development (CPRD), which focuses on the development of synthetic methodologies and processes across multiple modalities with a particular emphasis on ADCs/bioconjugates and oligonucleotides. /p h3Principal Scientist, Analytical Chemistry /h3 pAs a Principal Scientist, you will provide advanced analytical characterization and problem-solving to support chemical process development for new/complex modalities, with a current focus on ADCs/bioconjugates and oligonucleotides (incl. siRNA). You will operate as a scientific leader who partners closely with process chemists and cross-functional stakeholders, drive execution, prioritization, and clear communication of analytical strategy and results across projects, maintain an active hands‑on laboratory contribution, personally design and execute analytical experiments, troubleshoot complex problems, guide and mentor junior scientists and project analysts, and drive innovation growth through internal and external scientific networks, including collaborations with universities and external partners. /p h3Key Responsibilities /h3 ul liDevelop and apply fit‑for‑purpose analytical methods to characterize materials and address complex questions for ADCs/bioconjugates and oligonucleotides (incl. siRNA), supporting both portfolio delivery and investigations/troubleshooting. /li liLead advanced characterization strategies for complex modality questions in partnership with internal SMEs and cross‑functional teams, translating complex datasets into clear, actionable process insight to support decision‑making. /li liEnable portfolio delivery by acting as an analytical scientific lead across multiple projects and supporting planning, prioritization, timelines, and communication in project governance forums. /li liSustain an active hands‑on laboratory presence including method development and optimization and execution of analytical experiments, with accountability for data quality, documentation, and clear reporting. /li liMentor and coach colleagues; contribute to building sustainable capability and knowledge‑sharing within PAR. /li liLead innovation growth in this area by building strong internal and external scientific networks, including collaborations with universities and other external partners; actively adopt new technologies and approaches into PAR practice. /li liActively contribute to scientific excellence through publications/patents and a strong scientific track record, and represent PAR through internal and external scientific engagement. /li /ul h3Experience and Skills /h3 ul liEducation: PhD in Analytical Chemistry, Biochemistry, Biotechnology, Life Sciences, Pharmaceutical Sciences, or related discipline with 5+ years relevant industrial experience; or MSc with 9+ years relevant experience. /li liDeep expertise in analytical characterization of complex modalities, with relevant experience working with ADCs/bioconjugates and/or oligonucleotides. /li liDemonstrated hands‑on laboratory experience in developing, executing, and troubleshooting analytical methods for complex synthetic modalities. /li liStrong practical proficiency in analytical techniques relevant for complex modality characterization, including MS and LC‑based analytical techniques (e.g., LCMS/UPLC and appropriate LC modes such as RP/HIC/SEC/IEX as applicable). /li liExperience using HRMS to characterize oligonucleotides (including full‑length products and impurities) and ADCs/bioconjugates (intact mass, subunit analysis, and peptide mapping). /li liFamiliarity with complementary non‑MS methods (e.g., CE, spectroscopy, glycan profiling, or other assays supporting biologics development) is preferred. /li liExperience with residual protein and/or enzyme‑related analytics (e.g., residual enzyme determination, total protein quantification, or related approaches) is an asset. /li liInterest and some experience in small‑molecule and peptide analytics is preferred. /li liAbility to independently generate, interpret, and troubleshoot complex analytical data; strong scientific judgement and problem‑solving. /li liDemonstrated strength in project management, including design, prioritization, and delivery of analytical milestones in cross‑functional teams. /li liExcellent communication skills (oral and written), fluent in English; ability to translate complex analytical output into clear, actionable conclusions. /li liProven scientific track record (e.g., peer‑reviewed publications and/or patents/technical leadership). /li /ul h3Key Behaviours /h3 ul liA cooperative spirit in a diverse, multidisciplinary team is essential, with a strong emphasis on building deep connections and effective collaboration. /li liExhibits enthusiasm for laboratory work and a commitment to fostering teamwork and collaboration among all members. /li liDemonstrates critical thinking and creativity in addressing complex challenges. /li liProactive in identifying opportunities for improvement and receptive to new ideas and approaches. /li liExhibits flexibility by adjusting priorities and strategies to meet evolving project needs. /li liMentors colleagues in their areas of expertise and acts as a role model within the team. /li liAble to constructively challenge the status quo and advocate for innovative solutions. /li liFosters an inclusive environment that encourages diverse perspectives and new ideas. /li /ul h3Required Skills /h3 ul liBudget Management /li liChemistry, Manufacturing, and Control (CMC) /li liClinical Trial Protocols /li liCritical Thinking /li liCross‑Functional CollaborationDrug Discovery Development /li liIndustry Analysis /li liInterdisciplinary Work /li liMarket Research /li liOrganizing /li liPharmacokinetic Modeling /li liProcess Improvements /li liProduct Development /li liProduct Strategies /li liReport Writing /li liSafety‑Oriented /li liScientific Research /li /ul h3Preferred Skills /h3 ul liBudget Management /li liChemistry, Manufacturing, and Control (CMC) /li liClinical Trial Protocols /li liCritical Thinking /li liCross‑Functional Collaboration /li liDrug Discovery Development /li liIndustry Analysis /li liInterdisciplinary Work /li liMarket Research /li liOrganizing /li liPharmacokinetic Modeling /li liProcess Improvements /li liProduct Development /li liProduct Strategies /li liReport Writing /li liSafety‑Oriented /li liScientific Research /li /ul /p #J-18808-Ljbffr