Role Overview:
We are seeking a talented and detail-oriented Synthetic Chemist with demonstrated hands-on experience and expertise in peptide synthesis o support our expanding drug discovery programs. The successful candidate will contribute to the design, synthesis, purification, and characterization of peptides and peptidomimetics, working closely with multidisciplinary teams in a dynamic and collaborative environment.
Key Responsibilities:
* Design and execute solid-phase peptide synthesis (SPPS) using automated synthesizers and manual techniques.
* Develop and optimize synthetic routes for linear and cyclic peptides, including complex modifications and conjugations.
* Perform purification using preparative HPLC, SFC, MPLC chromatography, and other relevant techniques.
* Characterize compounds using HRMS, NMR, and other analytical tools.
* Collaborate with medicinal chemists and biologists to support SAR studies and lead optimization.
* Document experimental procedures and results in electronic lab notebooks (ELNs) and contribute to internal reports and publications.
* Ensure compliance with Eurofins’ quality standards and safety protocols.
Qualifications:
* Ph.D. or M.Sc. in Organic Chemistry, Medicinal Chemistry, or related discipline.
* Minimum 2–5 years of hands-on experience in peptide synthesis, preferably in a CRO or pharmaceutical setting.
* Proficiency with automated peptide synthesizers (e.g., Biotage, CEM Liberty Blue).
* Strong understanding of protecting group strategies, coupling reagents, and resin selection.
* Experience with peptidomimetics, macrocyclization, or conjugation chemistry is highly desirable.
* Experience in parallelization using automated platforms is also highly desirable
* Excellent problem-solving skills and attention to detail.
* Strong communication skills and ability to work effectively in a team-oriented environment.
Why Join Us:
* Work in a cutting-edge research environment with access to state-of-the-art facilities.
* Be part of a global scientific network with opportunities for growth and collaboration.
* Contribute to impactful drug discovery projects that advance human health.