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Biophysical & mass spectrometry scientist - gene therapy cmc

Braine-l'Alleud
Publiée le Publiée il y a 22 h
Description de l'offre

Make your mark for patients


We’re looking for a Biophysical Mass Spectrometry Scientist who is analytical, collaborative, and solutions-oriented to join our Gene Therapy Analytical Sciences team based at our UCB campus located in Braine-l’Alleud, Wallonia, Belgium.


About the role


In this role, you’ll lead the development and implementation of mass spectrometry and other biophysical methods to support the CMC development of recombinant AAV-based gene therapy products – from early clinical phases to launch readiness.

Key Responsibilities

1. Develop, validate, and transfer mass spectrometry and other biophysical assays for gene therapy products
2. Document protocols, procedures, and reports with high standards of data integrity
3. Manage laboratory activities and maintain a cutting-edge analytical environment
4. Collaborate cross-functionally with upstream/downstream/process/formulation teams, QC, vector biology, and external partners
5. Analyze and present results in team and project meetings
6. Ensure compliance with GMP, GSP, HSE, and biosafety standards

Qualifications

7. Master’s degree or engineering diploma in Analytical Chemistry, Biochemistry, or related field
8. 3+ years of industry experience in biophysical method development and validation
9. Proven hands-on expertise in mass spectrometry and liquid chromatography
10. Familiarity with Empower, Chromeleon, or Expressionist software
11. Experience with mass photometry is a plus
12. Strong experience in regulated lab environments (GLP/GMP), including documentation and HSE/Biosafety compliance
13. Knowledge of ICH Q14, Q2(R2), and Analytical Quality by Design principles
14. Excellent communication, critical thinking, and problem-solving skills
15. Fluency in English (written and oral) is mandatory


Are you ready to ‘go beyond’ to create value and make your mark for patients? If this sounds like you, then we would love to hear from you!

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