ATS Company: PA Solutions Requisition ID: 16835 Location:
Antwerp, Antwerp, BE, 2600
#job-location.job-location-inline { display: inline; } Date: May 30, 2026
MES Opcenter Pharma Engineer (m/f/d)
To support a large-scale Manufacturing Execution System (MES) transformation program at one of our Customers, we are looking for a Medior to Senior MES Opcenter Pharma Engineer (m/f/d).
You will play a key role in the design, configuration, validation, and deployment of Siemens Opcenter Execution Pharma within a GMP-regulated manufacturing environment. You will work closely with process experts, QA, IT, automation, and business stakeholders to translate manufacturing requirements into compliant and robust MES solutions.
Your responsibilities
MES Design & Implementation
1. Design, configure, and implement Siemens Opcenter Execution Pharma solutions aligned with shop-floor manufacturing processes
2. Translate User Requirements (URS) into functional and technical MES design
3. Configure electronic batch records (EBR), workflows, recipes, material tracking, and equipment modeling
4. Support integration with DCS/PLC systems, ERP (e.g. SAP), and other manufacturing systems
Project & Delivery Support
5. Participate in full MES project lifecycle: analysis, design, build, testing, deployment, and hypercare
6. Contribute to technical discussions with both business and IT stakeholders
7. Support system deployment across different manufacturing areas or sites (as applicable)
Validation & Compliance
8. Ensure MES solutions comply with GMP, GAMP5, and 21 CFR Part 11 requirements
9. Support CSV activities including risk assessments, specifications, test protocols, and deviation handling
10. Align with quality standards, SOPs, and validation frameworks
Testing & Go Live
11. Prepare and execute FAT/SAT, integration testing, and UAT support
12. Support manufacturing during go live and ramp up phases
13. Troubleshoot MES-related issues in collaboration with IT, QA, and operations
Collaboration & Knowledge Sharing
14. Act as a technical reference within the MES team
15. Coach and support more junior MES engineers (senior profiles)
16. Document solutions and contribute to standardization and best practices
Your profile
17. Sound experience of multiple years working with MES systems in a pharmaceutical or life sciences environment
18. Proven hands on experience with Siemens Opcenter Execution Pharma
19. Strong understanding of pharma manufacturing processes (batch manufacturing, materials management, equipment modeling)
20. Experience with MES integrations (ERP, automation, serialization is a plus)
21. Solid understanding of GMP, GAMP 5, and CSV principles
22. Familiarity with electronic records, audit trails, and system security concepts
23. Strong analytical and problem-solving skills
24. Able to communicate clearly with both technical and non technical stakeholders
25. Comfortable working in large, structured enterprise programs
26. Proactive mindset and ownership mentality
27. Business Fluency in English, able to communicate clearly with both technical and non technical stakeholders
28. Dutch/Flemish and French business fluency are advantage
Nice to Have / Assets
29. Experience working in large pharma programs
30. Experience with Siemens Opcenter Execution Core / MBR Designer
31. Knowledge of ISA 95 / ISA 88 concepts
32. Experience in multi-site MES rollouts
33. Previous exposure to DCS/PLC environments