Senior Bioinformatician – Translational & Clinical Development
Location: Belgium (Ghent area)
Employment Type: Full-time, client-embedded consultancy role
About the Role
A leading bioinformatics consultancy is seeking a Senior Bioinformatician to support Translational and Clinical Development programs within a global pharmaceutical environment. In this role, you will be embedded on-site in Belgium as part of a pharma client’s bioinformatics team, contributing to multiple clinical and translational programs focused on advancing novel therapies to patients.
You will apply advanced bioinformatics approaches to patient-level molecular and clinical data, enabling deeper understanding of disease biology, mechanisms of action, and clinical response.
Your Responsibilities
* Integrate, analyze, and interpret omics, translational, and clinical data from patient studies.
* Process and analyze complex molecular datasets, including bulk and single-cell RNA-seq, spatial transcriptomics, proteomics, and epigenomics.
* Design and maintain robust, reproducible bioinformatics pipelines suitable for clinical and regulatory contexts.
* Apply pathway, network, functional enrichment, and causal analysis methods to generate clinically relevant insights.
* Integrate omics data with clinical variables to identify biomarkers of response, safety, and patient stratification.
* Ensure data traceability, quality, and compliance with data governance and privacy requirements.
* Prepare high-quality analytical reports, visualizations, and presentations for multidisciplinary clinical and project teams.
* Contribute to internal documentation, study reports, and scientific publications.
Qualifications & Skills
Essential
* PhD or Master’s degree in Bioinformatics, Computational Biology, or a related field, with 5–10 years of experience in translational or clinical bioinformatics within an industry or consultancy setting.
* Strong expertise in patient-level omics data analysis, including single-cell and spatial technologies.
* Understanding of clinical study design, regulatory-compliant analysis, and data privacy considerations.
* Proficiency in R and/or Python; experience with HPC environments, cloud platforms, and containerization (e.g. Docker).
* Strong foundation in statistics, data mining, and data visualization.
* Ability to work independently while collaborating effectively in multidisciplinary teams.
* Excellent written and verbal communication skills and strong stakeholder management skills.
* Fluent in English.
Preferred
* Experience integrating omics and clinical data to inform biomarker hypotheses.
* Familiarity with FAIR data principles, reproducible research practices, and GxP environments.
* Background in disease biology (e.g. neurology, immunology, rare diseases).
* Contributions to peer-reviewed publications or clinical project reports.
What’s on Offer
* On-site role based in the Ghent area (Belgium).
* Direct involvement in clinical-stage translational research within a pharmaceutical setting.
* Exposure to cutting-edge omics technologies and patient-level data.
* Professional development through mentoring, training, and access to a strong expert network.
* Collaborative, impact-driven environment where your work supports real patient outcomes.
* Competitive compensation and benefits package.