Postdoctoral Position: Alternative Translational Models for Precision Medicine
KU Leuven is an autonomous university. It was founded in 1425. It was born of and has grown within the Catholic tradition.
The Alternative Translational Models group for Prevision Medicine and New Approach Methodologies focuses on developing and utilizing precision cut tissue slices on chip technology to create more accurate and physiologically relevant disease models for various applications. Our reserach involves using these models for toxicity screening, therapeutics evaluation, diagnostic applications, and more. We also conduct pharmacokinetics studies to better understand drug behavior in a complex, tissue-specific environment. The advertised position will specifically focus on the study of precision cut brain slices to develop drug delivery systems that can effectively cross the blood-brain barrier for the treatment of glioblastoma tumors in animal and patient tissue models. By bridging the gap between preclinical and clinical research, our work aims to enhance the precision and effectiveness of treatments, providing a more personalized approach to medicine.
Responsibilities
* Conduct 3D tissue culture.
* Lead studies involving nanomaterial toxicity and theranostic screening, particularly in the context of personalized medicine in glioblastoma tumor models.
* Perform animal in vivo studies and develop advanced 3D models for testing nanomaterial and other therapeutic interventions.
* Utilize in vivo optical imaging systems for real time monitoring of biological processes.
* Work with microfluidic systems (desirable but not must) as well as developing novel platforms to evaluate nanomaterials and drug behavious in complex biological systems.
* Supervise Phd and Masters students, providing guidance and mentorship.
* Contribute to the preparation and submission of research manuscripts for peer reviewed journal and dissemination of results in national and international conferences.
* Assist in the preparation of funding applications.
Profile
* Extensive experience working with cell culture and animal models.
* Ideally, experience working with 3D ex vivo models.
* Desirable experience working with mathematical modeling.
* A strong record of publications in peer reviewed journals and contribution to funding applications.
* Excellent verbal and written communication in English.
Offer
* Strong analytical and problem solving skills.
* Ability to work independently as well as part of a multidisciplinary team.
* Knowledge of mathematical models.
What We Offer:
* An opportunity to work with leading experiments in the field of alternative translational models, nanomedicine, and 3D models.
* Access to state of the art facilities and resources.
* A dynamic and collaborative work environment.
* Professional development opportunities and mentorship.
Interested?
KU Leuven strives for an inclusive, respectful and socially safe environment. We embrace diversity among individuals and groups as an asset. Open dialogue and differences in perspective are essential for an ambitious research and educational environment. In our commitment to equal opportunity, we recognize the consequences of historical inequalities. We do not accept any form of discrimination based on, but not limited to, gender identity and expression, sexual orientation, age, ethnic or national background, skin colour, religious and philosophical diversity, neurodivergence, employment disability, health, or socioeconomic status. For questions about accessibility or support offered, we are happy to assist you at this email address.
Postdoctoral Position: Alternative Translational Models for Precision Medicine
2025-08-07 23:59 (Europe/Brussels)
2025-08-07 23:59 (CET)
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