Within a Novalix insourcing team based in a pharmaceutical company, you will play a key role in the production of complex molecules to support drug discovery and development programs. You will join a small, dynamic and highly motivated team, committed to implementing new technologies and exploring innovative synthetic routes through passionate scientific exchange.
Responsibilities
* Conducting and supervising large-scale organic syntheses (up to several hundred grams) to deliver new chemical entities, advanced intermediates and key building blocks.
* Ensuring that all batches delivered meet the expected quantities, purities, timelines and quality standards required by the projects.
* Participating actively in the design, evaluation and optimization of synthetic routes, with a strong focus on robustness, reproducibility and scalability.
* Performing scientific and technological watch, using retrosynthetic analysis tools and literature data to propose and justify efficient and innovative synthetic routes.
* Identifying and addressing scale‑up challenges (reaction performance, safety, impurities, work‑up and purification).
* Contributing to the evaluation and, when relevant, implementation of new technologies (e.g. HTE, automation, flow chemistry…) as tools to accelerate route development and improve process robustness.
* Managing projects with a high level of autonomy, including planning of activities, prioritization, and regular scientific interactions with the client.
* Ensuring proper documentation, reporting and communication of results to management and to the client, in line with our standards.
* Contributing to a safe working environment by applying good laboratory practices and HSE rules.
Your projects may involve the reproduction, optimization and secure scale‑up of established synthetic routes, as well as the development of novel and innovative pathways to support therapeutic research programs.
Profile
You hold a PhD in organic chemistry with post‑doctoral and/or industrial experience, including relevant expertise in large‑scale synthesis. You are passionate about chemistry, scientifically curious and solution‑oriented, with a strong sense of responsibility.
* Your rigor, organization and autonomy.
* Your ability to manage several priorities in a project‑driven environment.
* Your team spirit and your ability to interact efficiently with clients and multidisciplinary teams.
* Your enthusiasm for new technologies and innovation.
* Your excellent scientific reporting and communication skills.
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