Principal Scientist, High-Throughput Analytical Chemistry
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Principal Scientist, High-Throughput Analytical Chemistry
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Join to apply for the Principal Scientist, High-Throughput Analytical Chemistry role at Johnson & Johnson
At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com
Job Function: Discovery & Pre-Clinical/Clinical Development
Job Sub Function: Pharmaceutical Product R&D
Job Category: Scientific/Technology
All Job Posting Locations: Beerse, Antwerp, Belgium
Job Description: The successful candidate will be employed in the department of Chemical Process Research & Development (CPRD). The CPRD organization focuses on developing synthetic methodologies and processes for small molecules, oligonucleotides, peptides, antibody-drug conjugates, and other emerging modalities. CPRD aims to provide world-class production processes of active pharmaceutical ingredients (APIs) by enhancing efficiency, safety, and cost-effectiveness. Its key objectives include refining synthetic routes, scaling up processes from laboratory to commercial levels, ensuring regulatory compliance, and minimizing environmental impact. Within this department, the Process Analytical Research (PAR) subdepartment plays a critical role in providing analytical data and expertise for all chemical process development activities. PAR ensures quality and performance through the design and implementation of state-of-the-art analytical methods while also generating and documenting essential end-to-end knowledge.
We currently have an open position for a Principal Scientist, High-Throughput Analytical Chemistry within the PAR team, specializing in analytics for biocatalysis and chemocatalysis high-throughput experimentation.
Job Description: As a Principal Scientist, you will focus on providing innovative analytical solutions to support high-throughput experimentation (HTE) in biocatalysis and chemocatalysis. Your role will involve developing methodologies and platforms that enable efficient analysis, reporting, and characterization of synthetic routes for small molecule production and related modalities.
Key Responsibilities:
* Develop and implement analytical methodologies to support HTE labs for biocatalysis and chemocatalysis.
* Build and oversee the analytical platform necessary for efficient HTE screenings.
* Demonstrate a strong knowledge of high-throughput technologies and the digital infrastructure required to integrate these technologies.
* Drive automation efforts to enhance laboratory efficiency and throughput.
* Contribute to the integration of artificial intelligence (AI) and machine learning (ML) methods to build end-to-end capabilities for high-throughput systems, including active learning to improve analytical performance and optimize experimental workflows.
Experience and Skills:
* A PhD in analytical chemistry, organic chemistry, biochemistry, (bio)chemical engineering, or relevant scientific disciplines with around 3 years of industrial experience, or a master's degree with 6 years of relevant experience.
* Expertise in high-throughput analytical techniques (e.g., ultrafast chromatography, high-speed mass spectrometry, plate-based spectroscopic measurements) and their application in biocatalysis, chemocatalysis, and related synthetic processes.
* Knowledge of digital infrastructure and automation technologies (e.g., plate handlers, liquid and solid dispensing systems, co-bots), including systems required to effectively integrate high-throughput analytical techniques, automation systems, and data management software capable of connecting plate design to analytical results in an end-to-end fashion.
* Interest and experience in AI/ML applications in research and development.
* Proven research track record supported by peer-reviewed publications.
* Excellent communication skills in English, both verbal and written.
Key Behaviours:
* Collaborative spirit within diverse, multidisciplinary teams, emphasizing building deep connections and effective collaboration.
* Enthusiasm for laboratory work and fostering teamwork.
* Critical thinking and creativity in solving complex challenges.
* Proactive in identifying improvement opportunities and receptive to new ideas.
* Flexible in adjusting priorities and strategies.
* Mentors colleagues and acts as a role model.
* Constructively challenges the status quo and advocates for innovation.
* Encourages diverse perspectives and new ideas in an inclusive environment.
Our Offer: An exciting role in an international, dynamic environment with continuous learning and growth. Opportunity to work with cutting-edge analytical technologies. Attractive remuneration with benefits like healthcare and work-life balance. A respectful, inclusive team environment valuing diversity.
Seniority level
* Not Applicable
Employment type
* Full-time
Job function
* Research, Analyst, and Information Technology
Industries
* Hospitals and Health Care
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