About the role
Argenx is establishing a new department dedicated to small molecule and peptide drug discovery. We are seeking a Senior Scientist in Medicinal Chemistry to play a pivotal role in shaping this capability and advancing preclinical projects. This position offers the opportunity to influence strategy, drive innovation, and deliver high-quality drug candidates that make a real impact.
This position is based at our facility in Zwijnaarde (Ghent), and expects on-site presence.
Key Responsibilities
1. Lead Discovery Projects: Partner with lead biologists to progress programs from hit identification through to clinical candidate nomination, ensuring timely delivery of high-quality candidates.
2. Design and Optimise Molecules: Collaborate with CROs and expert consultants to design novel compounds addressing identified challenges and improving candidate profiles.
3. Cross-Functional Collaboration: Work closely with internal experts in computational chemistry, ADME/Tox, IP, CMC, and pharmacology to integrate multidisciplinary insights.
4. Innovation & Technology: Stay at the forefront of developments in small molecule and peptide therapeutics. Champion the use of AI, machine learning, and in silico approaches to accelerate design–make–test–analyse cycles.
5. Data Management: Establish efficient workflows for capturing, integrating, and analysing data from multiple partners.
6. Communication: Provide clear updates on progress, challenges, and solutions to stakeholders and project teams.
Profile
7. PhD (or equivalent) in a relevant chemical science, with 8+ years of experience in biotech or pharma.
8. Proven track record in design and synthesis of small molecules, with experience advancing projects to preclinical development.
9. Ability to work independently and collaboratively within a team.
10. Excellent communication skills, capable of presenting complex scientific concepts to diverse audiences.
11. Fluent in written and spoken English to ensure clear and effective information exchange.
12. Demonstrated ability to take initiative and address challenges proactively.
13. Dynamic and practical problem-solving approach with a focus on delivering tangible results.
Offer
14. The opportunity to establish a new role within the organization, contributing to shaping its future direction.
15. A competitive salary package accompanied by comprehensive benefits.
16. Working in a human-sized, dynamic, rapidly growing biotech company, providing an engaging work environment.
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