Atargenx,we’reall in on our innovation mission to transform care for people living with severe autoimmune diseases. We speak the language of science, put patients first, and value high‑impact over hierarchy. If you’re energized by bold ideas and collaborative problem‑solving—patients are waiting.
The opportunity
You will serve as aBiomarkerBiostatisticsLeadsupporting autoimmune clinical development programs from early to late phase, including translational andreversetranslationalactivities. In this role, you will providescientific and statistical leadership for biomarker strategies, ensuring that analyses are methodologically sound, interpretable, and aligned with clinical questions and developmentobjectives. You will contribute tobiomarkerdrivenstudy designs, integrated clinical–biomarkeranalyses andevidence generation, and the advancement ofreproducible quantitative practicesacross the portfolio.
Whatyou’lldo
1. Lead biomarker biostatistics across clinical development programs.Translate clinical and translational questions intowelldefinedstatisticalobjectives; design, justify, and execute robust analyses (e.g.longitudinal andrepeatedmeasuresmodels,timetoeventanalyses, multiplicity control); interpret results in the context of clinical relevance and programdecisionmaking.
2. Act as the primary statistical partnerfor Clinical, Biomarker, and Translational teams onbiomarkerrelatedtopics, contributing toexperimentaldesign, biomarker sampling strategies, statistical sections ofbiomarkerdocuments, and integratedanalysis andinterpretation of clinical and biomarker data.
3. Provide statistical oversight of exploratory and translational biomarker analyses, includingsingle,complex andhighdimensionaldatasets, ensuringappropriate QC, normalization, sensitivity analyses, and transparent reporting.
4. Support biomarker utility assessment(e.g.exploratory, pharmacodynamic, prognostic, predictive) and contribute to discussions on biomarker qualification, interpretation, and readiness for clinical or regulatory use where applicable.
5. Ensure reproducibility, traceability, and data integrityof biomarker analyses in collaboration with Biomarker Data Management and Statistical Programming, aligned with ALCOA++ principles and regulatory expectations.
6. Contribute to clear and consistent reportingthroughhighqualitytables, listings, figures, andwelldocumenteddashboards that support governance, clinical interpretation, andcrossstudylearning.
7. Mentor and influence, promoting sound statistical reasoning, best practices inRbasedanalysis, and consistency in biomarker analysis approaches across programs.
8. Represent biomarker biostatisticsincrossfunctional, governance, and (asappropriate)regulatory interactions, consistent with senior biostatistics leadership responsibilities.
Whatyou’llbring
9. Advanced degree inBiostatistics, Statistics, or a closely related quantitative discipline;8+ years of experiencein pharma or biotech, with a strong focus on clinical development.
10. Deepexpertisein statistical methods for clinical and biomarker data, including longitudinal modeling, survival analysis, multiplicity adjustment, and robust inference across diverse biomarker endpoints.
11. Proven experience withdiagnostic,pharmacodynamic, prognostic, predictive, and/or surrogate biomarkers, ideally within autoimmune or immunology programs; experience supporting regulatory biomarker strategy is a plus.
12. Highproficiencyin Rfor statistical analysis, reporting, and reproducible workflows; familiarity with Bioconductor or otherbiomarkerrelevantpackages is valued.Python and/orSAS experience is an advantage.
13. Strong ability toclearly communicate statistical concepts and resultstononstatisticiansand senior decisionmakers, both in writing and in discussion.
14. Experience working withCDISC standards (SDTM/ADaM)and contributing tosubmissionreadyorinspectionreadyanalyses.
15. Experience withversioncontrolled, collaborative analysis environments(e.g.Gitbasedworkflows) and good documentation practices.
16. Experience withdata visualization or dashboarding(e.g.R/Shiny, Spotfire, or similar) to support clinical interpretation.
17. Onsite presence in the Ghent office for2 days per week.
Whyargenx
We dare to do more—together. Atargenxyou’lljoin a global immunology biotech where the science of co‑creation drives bold goals and real patient impact. You’llfind high‑impact over hierarchy, and a culture where Argonauts collaborate across borders to turn precision science into medicines.
Offer
18. Member of a cross-disciplinary team involved in clinical development of therapeutic antibodies.
19. Opportunity to contribute to the continued build-out of the TranslationalDataScience team.
20. Competitive salary package with extensive benefits.
Apply
Your application and related information will remain strictly confidential.
The annual base salary hiring range for this position is €100,000.00 - €137,500.00 EUR
This job is eligible to participate in our short-term and long-term incentives program.
The hiring range displayed above is the range of possible base pay compensation that argenx believes in good faith it will pay for this role at the time of this posting. The hiring range is based on the job grade for this position. Individual compensation paid within this range depends on a variety of factors, including, but not limited to, internal equity, prior education and experience, job-related knowledge and demonstrated skills. argenx may pay more or less than the posted range and this range may be modified in the future.