Location
Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed.
Opportunity
Praxis Precision Medicines is building a strong pipeline of Software Engineering talent to support the continued evolution of our eDiary and clinical data platforms. Engineers in this role will first contribute to and grow within our eDiary ecosystem—a regulated, patient-facing platform used across our Epilepsy portfolio. Our engineers work across modern web and mobile applications, secure clinical data platforms, cloud infrastructure, distributed system architectures, API design, auditability frameworks, identity and access control systems, and production observability. When you apply to this position, your profile will be considered for current and future Software Engineer openings supporting the eDiary platform and adjacent clinical systems.
Primary Responsibilities
* Design, develop, and maintain reliable, production‑grade code across frontend, backend, and data layers, implementing software solutions that meet clinical, operational, and regulatory requirements.
* Deploy and operate services in a cloud environment (AWS preferred) and contribute to architecture and design reviews with a focus on reliability, scalability, and security.
* Debug and resolve production issues across distributed and asynchronous workflows; diagnose performance bottlenecks; and own incident response, including root cause analysis and durable fixes that prevent recurrence.
* Collaborate with QA, Clinical Operations, Clinical Development, Product, and IT stakeholders to translate requirements into validated releases.
* Design APIs and data models that preserve audit trails, version history, and system traceability; and improve system observability through structured logging, monitoring, and alerting.
* Uphold high standards for data integrity, security, and regulatory compliance across all systems.
Qualifications and Key Success Factors
* Bachelor’s degree in Software Engineering or equivalent practical experience.
* 3+ years of non‑internship professional software development experience, with demonstrated ability to design, build, and operate production software systems end‑to‑end.
* Demonstrated experience using AI‑assisted development tools (e.g., code generation, automated testing, debugging copilots) to improve engineering productivity and code quality, with ability to critically evaluate AI‑generated outputs for correctness, security, and maintainability.
* Strong foundation in software engineering fundamentals: data structures and algorithms, API and interface design, relational data modeling and transactional integrity, and separation of concerns.
* Demonstrated ability to debug complex issues across multiple layers (client, API, database, infrastructure) and trace issues in distributed or asynchronous systems using logs, metrics, and instrumentation.
* Experience deploying and operating applications in a cloud environment (any major provider), including networking, access control, configuration, and monitoring; and experience designing secure systems including authentication and authorization flows.
* Experience implementing production‑grade monitoring, alerting, and CI/CD practices; and ability to work effectively in a remote‑first, high‑accountability environment.
* The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You’ll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions.
Preferred Qualifications
* Experience building systems with offline behavior, synchronization logic, or conflict resolution.
* Experience designing for auditability, traceability, or immutable data models; or operating systems in regulated or compliance‑driven environments.
* Experience containerizing and deploying services; building modern web applications (TypeScript and React preferred); and integrating with third‑party systems or external APIs.
A Day in the Life
On a typical day as a Praxis Software Engineer, you might: start with a team sync to align on sprint priorities and release readiness; review requirements with Clinical or QA partners to clarify edge cases; write and test code for a new feature in the eDiary web or mobile application; deploy a service update to the cloud and verify monitoring instrumentation; trace a production issue across client logs, backend APIs, and database queries; perform root cause analysis and implement a long‑term fix; participate in a design discussion focused on improving auditability or system reliability; review pull requests and provide structured technical feedback; document logic changes to support validation traceability; and participate in on‑call or release‑readiness support.
About the Team
The Praxis Software Engineering team operates in a fast‑paced, remote, high‑accountability environment where engineers own their systems end‑to‑end, from design and implementation through deployment and ongoing production operations. Engineers may contribute to patient‑facing platforms, clinical systems, financial infrastructure, commercial systems, or other enterprise applications. Regardless of domain, quality, data integrity, and reliability are non‑negotiable. This role includes active production support responsibilities; ownership extends beyond feature delivery to sustained system reliability, observability, and operational excellence.
Company Overview
Praxis Precision Medicines is a clinical‑stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. Our core values of Trust, Ownership, Curiosity, and Results guide every aspect of our business.
Diversity, Equity & Inclusion
We are an equal‑opportunity employer and are committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service, veteran status, or any other characteristic protected by law.
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